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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. Which statement best describes current recommendations on postnatal corticosteroids in neonatal Broncho pulmonary dysplasia?

A) Early, low-dose, short-course hydrocortisone therapy may be beneficial.
B) High-dose dexamethasone is routinely and strongly recommended.
C) Combination of dexamethasone and hydrocortisone long-term therapies is advised.
D) Late and long-term hydrocortisone therapy may be warranted.

2. Which of the following components of a grant proposal defines the study hypothesis?

A) Research design
B) Background
C) Specific aims
D) Significance

3. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?

A) 14
B) 3
C) 8
D) 1

4. A 72-year-old patient, weighing 72 kg and measuring 173 cm tall, presents to the emergency department with an acute ischemic stroke. The symptoms have been present for just over an hour. The patient has a history of hypertension and is currently taking lisinopril 10 mg daily.
The patient's evaluation reveals no intracerebral hemorrhaging. The current BP is 178/100 mm Hg. It is now 150 minutes from stroke symptom onset.
Which of the following should now be administered?

A) An antihypertensive; reconsider intravenous t-PA once BP decreases
B) Intravenous-PA
C) An antihypertensive; reconsider intra-arterial thrombolytics once BP decreases
D) Intravenous glycoprotein IIb/IIIa inhibitor

5. A 45-year-old patient develops neutropenia, fever, headache, meningismus, and lethargy after induction chemotherapy for acute lymphocytic leukemia. A lumbar puncture reveals 1,000 total nucleated cells with elevated CSF protein with gram stain showing Gram-positive rods. Which of the following is the best initial empiric therapy for this patient?

A) Ampicillin and cefotaxime
B) Ceftriaxone
C) Ampicillin
D) Ceftazidime and gentamicin

Solutions: